Complement and clot

Clot retraction facilitates clot lysis.

Platelet facilitation of clot lysis was studied using the dilute clot lysis assay, a standardized assay for fibrinolysis shown to correlate with the development of postoperative deep vein thrombosis. Clots prepared from dilute platelet poor plasma showed prolonged clot lysis when compared with clots prepared in a similar fashion from dilute platelet rich plasma. Since in the presence of platele...

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

The complement and coagulation systems closely interact with each other. These interactions are believed to contribute to the proinflammatory and prothrombotic environment involved in the development of thrombotic complications in many diseases. Complement MASP-1 (mannan-binding lectin-associated serine protease-1) activates coagulation factors and promotes clot formation. However, this was mai...

Clot firmness.

Clot control

For neurons, overexcitement is deadly. To avoid this, brain cells must sop up unneeded neurotransmitters from the synapse through membrane-bound transporters. If these transporters fail, neurons and other brain cells get excited to death—a phenomenon that may contribute to brain damage during stroke and Alzheimer's disease. Indeed, brain deterioration after stroke is associated with elevated le...

Electrolytic resistance of the blood clot; resistance clotting time, onset of clot retraction and the clot resistance.

I N THE previous paper a technique for the determination of the electrolytic resistance of the blood clot was presented (I). The present paper deals with the variations in the electrolytic resistance of the blood clot over a 40. to &-hour period, and with the physiological significance of certain measurements of the resistance. The curve of the resistance against time will be called the electro...